Dietary precautions and contraindications while taking Tilpotide/Tisiparatide (Mufengda)

While taking Tirzepatide/tirzepatide (Tirzepatide), the patient's dietary management is crucial to the therapeutic effect and safety. First of all, you should maintain a balanced diet and avoid excessive intake of high-sugar and high-fat foods. Although tilsiparatide has hypoglycemic and weight-loss effects, excessive sugar intake may weaken the effect of the drug and increase the risk of blood sugar fluctuations. It is recommended to consume more foods rich in dietary fiber and low glycemic index, such as whole grains, vegetables and fruits, to assist blood sugar control and weight management.

Patients should pay attention to the reasonable arrangement of meals and food intake while taking the medicine. Because tisiparatide may cause nausea, vomiting, or loss of appetite, it is recommended to divide daily meals into small and frequent meals to avoid eating too much at one time. Drinking moderate amounts of water before or with meals can also help reduce gastrointestinal discomfort. For patients with gastroparesis or digestive dysfunction, their diet structure and eating speed should be adjusted under the guidance of a doctor to ensure balanced nutritional intake.

Concomitant consumption of highly alcoholic beverages needs to be avoided. Alcohol can affect blood sugar levels and may worsen gastrointestinal side effects of tilsiparatide, such as nausea, diarrhea, or vomiting. For patients with drinking habits, alcohol intake should be strictly controlled and drinking should be suspended when necessary to reduce the risk of hypoglycemia and gastrointestinal discomfort. In addition, caffeinated and stimulating drinks should also be consumed in moderation to reduce heart palpitations and gastrointestinal reactions.

Patients should follow individualized dietary principles and adjust their diet plan based on blood glucose monitoring results. For patients at high risk of hypoglycemia, the intake of complex carbohydrates or protein can be increased under the guidance of a doctor to stabilize blood sugar. Long-term adherence to a healthy diet and lifestyle can help improve the efficacy of tisiparatide, reduce side effects, and achieve better overall results in diabetes and obesity management.

Reference materials:https://www.ncbi.nlm.nih.gov/books/NBK585056/