What is the recommended dosage time for Alpelisib?

Alpelisib (Alpelisib)-Piqray, as an inhibitor targeting PI3K, is usually used to treat advanced breast cancer, especially patients with PIK3CA mutations. In order to ensure maximum efficacy and reduce side effects, correct medication time and usage are very important. According to the Medication Guide for Apelvis, the optimal dosing time is 300 mg taken orally once daily, usually two 150 mg film-coated tablets, taken with food.

Apelix should be taken orally at a fixed time every day, preferably at the same time every day, to help maintain stable drug concentrations in the body. In order to improve the absorption of the drug, Apelix is u200bu200brecommended to be taken with food. Food can help increase the bioavailability of the drug, thereby improving its efficacy. Taking it on an empty stomach may affect the absorption of the drug, resulting in reduced efficacy. Therefore, it is recommended that patients take medications after meals to avoid interference between food and medications.

Treatment with apelvis is usually continued until disease progression or unacceptable side effects occur. For most patients, treatment may last several months or even longer. During treatment, patients should regularly undergo relevant tests, such as blood sugar, liver function, hematology tests, etc., to monitor possible adverse reactions during treatment.

Patients should adhere to the medication according to their doctor's recommendations while receiving treatment and closely monitor for any possible side effects. If discomfort occurs during treatment, the patient should report it to the doctor promptly so that appropriate adjustments can be made.

In general, the best time to take Apelvis is to take 300 mg orally once a daywith meals, and maintain a fixed dosage time every day. This method of administration helps ensure drug efficacy and patient tolerance. During the treatment process, patients should cooperate closely with their doctors to ensure the smooth implementation of the treatment plan.

Reference materials:https://www.ncbi.nlm.nih.gov/books/NBK574353/