Precautions and safety tips for taking Anamorelin

Anamorelin (Anamorelin) is a drug that activates the growth hormone secretory receptor (GHS-R1a) and is mainly used to relieve symptoms of cancer cachexia, such as loss of appetite and weight loss. It works on the appetite center of the brain to promote appetite, thereby improving the patient's weight status. However, although anamorelin has certain efficacy in alleviating the symptoms of cancer-related cachexia, there are some dosage precautions and safety tips that need to be paid special attention to when using it.

The use of anamorelin is not suitable for all types of patients, especially those who have difficulty taking food orally or have poor digestion and absorption of food. For these patients, since anamorelin mainly works by increasing appetite and promoting eating, if the patient is unable to eat or digest food normally, the effect of anamorelin may be limited and may even increase the patient's discomfort. Therefore, doctors often advise such patients to avoid anamorelin and instead seek other treatment options.

In addition, the use of anamorelin also needs to consider the patient's liver and kidney function. In some patients with impaired hepatic or renal function, the metabolism and excretion of anamorelin may be affected, so a detailed assessment of the patient's hepatic and renal function status is required before use. In these patients, anamorelin should be used with caution and close monitoring for possible side effects is required. If the patient develops abnormal liver function or renal insufficiency, the drug dosage should be adjusted promptly or use should be suspended.

Anamorelin side effects include gastrointestinal upset, such as nausea, vomiting, and diarrhea. Therefore, when using anamorelin, patients should gradually adjust the dose according to the doctor's recommendations to reduce the occurrence of side effects. If patients experience severe gastrointestinal discomfort or other adverse reactions, they should stop using the drug immediately and seek medical help.

Reference materials:https://pins.japic.or.jp/pdf/newPINS/00069223.pdf