Whether aprocitentan is included in medical insurance and its reimbursement ratio and self-payment

Aprocitentan (aprocitentan) has not yet been officially launched in China, so it is naturally not included in the national medical insurance catalog, and there is no policy support such as medical insurance reimbursement ratios. For patients who need the drug, they can only obtain drug information through some compliant overseas medical service channels for the time being, and cannot purchase it in domestic hospital pharmacies. Since registration and approval has not been completed in China, patients must be evaluated by a doctor before use to ensure clear indications and understand possible risks and alternative treatment options to avoid safety risks caused by purchasing medicines on their own.

Since aprexitentan is not covered by medical insurance, all costs are borne by the patient. At present, the original drug is not popular in overseas markets, but Laos has a officially launched generic version of Aprecitentan. The drug ingredients are consistent with the original drug and are used to meet the clinical needs of the local and surrounding countries. According to the latest market conditions, the price of this Lao generic drug is relatively low, only a few hundred yuan per box, which is significantly lower than most innovative cardiovascular drugs that have not yet been launched in the country. However, the actual purchase price may be affected by factors such as exchange rate fluctuations, channel service fees, and transportation costs, and therefore may vary slightly in different time periods.

For patients who need to obtain aprecitentan through overseas channels, it is recommended to give priority to legal and compliant channels authorized by international pharmaceutical companies and avoid personal channels from unknown sources or unqualified platforms to reduce the risk of buying counterfeit drugs, inferior drugs, or drugs that are damaged in transportation. Formal international pharmacies or cross-border medical platforms usually provide batch numbers, manufacturer certificates, complete packaging and transportation cold chain information to help patients ensure the quality of medicines. At the same time, it should be noted that purchasing drugs overseas is an act of self-payment. All costs cannot be reimbursed by medical insurance, and there is no drug protection system under domestic laws. Therefore, the costs and risks need to be fully assessed before use.

Generally speaking, aprecitentan has not yet entered the domestic market and does not currently support medical insurance payment in China. If patients really need to use this drug, they need to have their condition comprehensively evaluated by the attending doctor and then obtain the generic version at their own expense through reliable overseas channels. Although the price of the Lao version of generic drugs is relatively acceptable at a few hundred yuan, it still needs to be used under the guidance of a doctor, and the efficacy and safety must be monitored regularly to ensure that the treatment process is both economical and safe.

Reference materials:https://pubmed.ncbi.nlm.nih.gov/40853274/