How to follow and implement the usage and dosage of Besudil/Elac

Belumosudil mesylate tablets (Belumosudil) is an oral immunomodulatory drug mainly used to treat chronic graft-versus-host disease (cGVHD). The recommended usage and dosage is: 200 mg orally once a day, and treatment is continued until symptoms of chronic GVHD progress or the patient requires new systemic treatment.

When using Besudil, patients should strictly follow the dosage requirements in the doctor's instructions and drug instructions. Besudil dosage adjustments are based primarily on patient-specific response and tolerability. The initial recommended dose is 200 mg once daily, but in individual cases, doctors may adjust the dose or treatment plan based on the patient's specific situation. The taking time of the drug should be fixed as much as possible and taken at the same time every day to ensure stable blood concentration of the drug and avoid missing doses.

Besudil is administered as an oral tablet. Patients should swallow the tablet whole and avoid chewing or crushing the tablet. In order to ensure the absorption effect of the drug, it is recommended that patients take it after meals to reduce the possibility of gastrointestinal discomfort. If the patient misses a dose, it should be refilled according to the doctor's instructions. If you miss a dose for an extended period of time, do not increase your dose on your own. Instead, continue taking your medication at your normal dose and schedule.

During the treatment process, patients need to undergo regular blood tests and monitoring of related physiological indicators so that doctors can detect any adverse reactions or changes in drug effects in a timely manner. During the use of Besudil, doctors will also make necessary adjustments to the treatment plan based on the patient's response.

Patients should avoid concomitant use with other immunosuppressive drugs unless approved by their physician. Besudil may interact with certain medications, so inform your doctor of all medications you are taking, including prescription drugs, over-the-counter drugs, and herbal supplements, before starting use.

Reference: https://www.drugs.com/pro/rezurock.html