Deuterated colexitinib (decavatinib) oral dosage form instructions and storage methods

Deucravacitinib is an oral small molecule selective TYK2 inhibitor mainly used to treat moderate to severe plaque psoriasis and some autoimmune diseases. Its oral dosage form is usually tablets, which are convenient for patients to take daily and avoid the inconvenience of injection or intravenous administration. The tablet design takes into account the patient's needs for long-term maintenance treatment. The dose is relatively fixed, ensuring that stable blood concentration and sustained efficacy can be achieved by taking it once a day or as directed by the doctor.

In terms of taking method, deuterated colexitinib tablets can be taken orally with meals or on an empty stomach, but it is recommended to take them at the same time every day to maintain the stability of blood concentration. For patients with gastrointestinal sensitivities, taking the medication after a meal may be an option to reduce mild discomfort, such as nausea or abdominal discomfort. The drug should be swallowed whole and should not be broken or chewed to ensure the complete efficacy and sustained-release characteristics of the drug.

In terms of storage, deuterated colexitinib tablets should be placed in a dry, cool environment, away from direct sunlight. It is usually recommended to store at room temperature (approximately 15–25°C). Medicines should be placed in their original packaging and protected from moisture, heat or strong light to ensure drug stability and efficacy. Keep away from children and pets at home to prevent accidental ingestion or contact.

In addition, patients should pay attention to the expiration date and packaging integrity of the drug during long-term use, and do not use tablets that have exceeded the expiration date or are damaged. If the medicine is found to be damp or discolored, it should be replaced in time. Correct medication and storage methods not only ensure the efficacy of deuterated colexitinib, but also help maintain the safety and stability of long-term treatment, thereby achieving the best clinical effect.

Reference materials:https://www.nlm.nih.gov/