Does cabergoline cause allergic reactions and how to deal with them

Cabergoline (Cabergoline) is a dopamine receptor agonist mainly used to treat prolactinemia and related pituitary tumors. Although most patients tolerate cabergoline well, some people may develop allergic reactions. Allergic reactions may manifest as rash, itching, hives, edema of the face or limbs, etc., and may also be accompanied by mild respiratory symptoms, such as throat tightness or nasal congestion. In rare cases, severe allergies may cause difficulty breathing or shock, which is a medical emergency.

一旦患者出现轻中度过敏症状，应立即停止服用卡麦角林，并向医生报告。 Depending on your symptoms, your doctor may prescribe antihistamines or topical skin treatments to relieve itching and redness. Usually, mild to moderate allergies can gradually resolve within a few days after stopping the drug or using adjuvant treatment, and will not cause serious effects on long-term health. Patients should pay attention to the changes in their skin and mucous membranes during use, especially in the first few weeks of initial medication.

For severe allergic reactions, such as difficulty breathing, significant swelling of the face or tongue, hives all over the body, or a sudden drop in blood pressure, call an emergency number or go to the emergency room immediately. Such cases may require intravenous epinephrine, corticosteroids, or antihistamines, and treatment under hospital supervision. After severe allergy occurs, cabergoline should usually be permanently discontinued and the need for alternative treatment options evaluated.

In clinical practice, in order to reduce the risk of allergy, doctors generally start with a low dose when patients first use cabergoline and gradually adjust it to a maintenance dose. At the same time, patients should inform their doctors of allergy history or allergic reactions to other drugs so that individualized medication can be provided. Strict compliance with medical instructions, timely monitoring of symptoms of discomfort, and reasonable handling of allergic reactions are key measures to ensure the safe use of cabergoline.

Reference materials:https://www.fda.gov/