Are there any dietary restrictions and precautions required while taking Eltrombopag (Revlan)?

During the period of taking Eltrombopag (Eltrombopag), dietary management has a certain impact on drug absorption and efficacy. Eltrombopag is an oral thrombopoietin receptor agonist, mainly used to treat immune thrombocytopenic purpura (ITP) and other thrombocytopenia-related diseases. This drug is easily affected by metal ions such as calcium, magnesium, aluminum and iron during the gastrointestinal absorption process. Therefore, patients should try to avoid ingesting foods or drugs with high content of these ingredients before and after taking the drug, so as not to reduce the drug absorption rate and affect the platelet-increasing effect.

Specifically, high-calcium dairy products, calcium-fortified beverages, iron-rich supplements, and certain antacids may interfere with the absorption of eltrombopag. To maximize drug efficacy, patients are advised to keep eltrombopag at least 2 hours apart from such foods or medications. In addition, you can choose to take the medicine on an empty stomach or with a small amount of low-calcium meal, which can improve the absorption efficiency of the medicine in the intestines. Properly arranging meal times can help ensure stable blood drug concentration, thereby improving platelet production.

In addition to dietary taboos, patients should also pay attention to overall lifestyle habits and the management of potential adverse reactions during medication. Eltrombopag may cause abnormal liver function, headache, fatigue or gastrointestinal discomfort, so blood routine and liver function indicators should be monitored regularly during treatment. If obvious discomfort occurs, you should report it to your doctor in time, and adjust the dosage or take corresponding treatment measures according to the doctor's instructions. At the same time, the concurrent use of other drugs that may increase the risk of bleeding or blood clots, such as aspirin or oral anticoagulants, should be avoided unless used under the guidance of a physician.

In general, there are no strict dietary restrictions during eltrombopag treatment, but attention should be paid to avoiding foods and drugs that are high in calcium, high in iron, or that affect drug absorption, and to maintain a reasonable medication interval. At the same time, regular monitoring of blood routine and liver function, paying attention to adverse reactions, and following the doctor's life and drug guidance can effectively improve the efficacy and reduce risks. By scientifically managing diet and living habits, patients can achieve stable platelet improvement within a safe range and improve their quality of life.

Reference materials:https://www.drugs.com/