Vorasidenib-VORANIGO official drug purchasing channels and precautions

Vorasidenib (trade name VORANIGO) is an oral IDH1/2 inhibitor, mainly used to treat IDH mutation-related low-grade gliomas and certain hematological tumors. Since the drug is not yet on the market in China and is not covered by medical insurance, patients cannot obtain it directly through domestic hospitals or pharmacies. If domestic patients want to use vorsidenib, they need to obtain it through formal overseas drug purchase channels or participate in clinical trials, and they need to be treated under the guidance of professional doctors.

In overseas markets, the original version of Voxanib is mainly available in the United States. The specification is 40mg*30 tablets. Each box sells for about 38 RMB, which is relatively expensive. For patients with limited financial ability, there are also some overseas generic drugs available, such as the same-specification generic version of Voxanib produced by Lucius Pharmaceuticals in Laos, which costs about more than 7,000 yuan per box. The ingredients of these generic drugs are basically the same as those of the original drugs, but when purchasing, you need to ensure the formal channels to ensure the quality and safety of the drugs.

Formal drug purchasing channels include purchasing through international drug import companies, purchasing prescriptions from overseas hospitals, or participating in international clinical trials. When choosing channels, patients should strictly abide by laws and regulations, ensure that the sources of drugs are legal, and avoid obtaining drugs through informal channels to prevent health risks caused by counterfeit drugs or substandard quality. At the same time, doctors will formulate a personalized medication plan based on the patient's specific condition and IDH mutation type, including dosage, medication cycle and combination medication regimen, to ensure drug efficacy and safety.

When using vorsidenib, you also need to pay attention to drug side effects and interactions. Common side effects include nausea, fatigue, abnormal hematological indicators, etc. Some patients may need to regularly monitor liver function, hematological and imaging indicators. Patients should strictly follow the doctor's instructions to take the medication and avoid adjusting the dosage or stopping the medication on their own to prevent a rebound of the condition or a decrease in efficacy. At the same time, during the period of drug use, communication with the attending doctor should be maintained and adverse reactions should be reported in a timely manner to ensure that the treatment process is safe and effective.

Reference materials:https://www.drugs.com/