How many tablets does a box of Shafinamide Tablets (Siddaco) contain and the detailed description of packaging of different specifications?

Safinamide tablets (Safinamide) are an oral drug mainly used to treat patients with Parkinson's disease, especially those in the mid-to-late stage who experience the "on-off" phenomenon during combined dopamine replacement therapy. Its mechanism of action includes selective monoamine oxidaseB (MAO-B) inhibition and modulation of glutamatergic nerves, thereby improving motor function and reducing motor fluctuations. Safinamine is sold in both domestic and foreign markets, but there are certain differences in specifications and prices.

In the domestic market, safinamide is already on the market. Currently, the package provided is 30 tablets per box, which is suitable for patients' daily short-term medication or adjusting the dosage according to the doctor's plan. The domestic price is approximately 1,600 multiple RMB per box, but it is not yet included in the medical insurance reimbursement items, so patients need to purchase it at their own expense. The domestic version facilitates short-term use and follow-up adjustments for patients, and also helps evaluate drug efficacy and tolerability in the early stages of treatment.

The specifications of safinamine tablets in overseas markets are different, mostly 100 tablets per box. Taking the original drug marketed in Europe as an example, the price per box of 100 tablets is about 5,000 RMB. The price is higher than that in China, but it is suitable for long-term treatment, especially for patients with mid-to-late Parkinson's disease who need to continuously maintain drug concentration. The original drugs have been rigorously verified in terms of efficacy and safety data, providing reliable protection for patients.

At the same time, a number of generic drugs have appeared in overseas markets, such as the Indian version of safinamide, which costs only about 400 RMB per box of 100 tablets, and the drug ingredients are basically the same as the original drugs. Generic drugs are more affordable and provide an economically viable option for patients who pay for themselves or take drugs for a long time. However, formal channels should be chosen when purchasing to ensure drug quality and safety. During use, patients still need to follow medical advice, take medications on time, and regularly monitor their condition and possible adverse reactions.

Reference materials:https://www.drugs.com/