Dali Leisheng (Keweike) prolongs sleep duration effect and usage guide

Daridorexant is a dual orexin receptor antagonist (DORA) that blocks the activity of Orexin-1 and Orexin-2 receptors, inhibiting arousal signals, thereby helping patients fall asleep and maintain sleep. Unlike traditional benzodiazepine sleeping pills, Dalitrazolin does not directly act on GABA receptors. Therefore, while extending the duration of sleep, it has less impact on cognitive function and next-day sleepiness, and is suitable for patients with long-term insomnia.

Clinical studies have shown that taking Dalilaysan once a day can significantly extend the total sleep time (TST) and reduce the number of nighttime awakenings. In a multi-center randomized controlled trial, after patients used it for 4 weeks, their total sleep time was extended by an average of about 60 minutes, and the number of nighttime awakenings was reduced by about 50%. For patients with insomnia who have difficulty falling asleep or wake up early, DaliRasen not only increases the total sleep duration, but also improves sleep continuity and quality, and enhances daytime alertness and quality of life.

The recommended adult dose is 10mg to 25mg, taken orally once every night before going to bed, and can be adjusted appropriately according to the patient's tolerance and clinical response. Medications should be taken within 30 minutes of bedtime and ensure at least 7 hours of sleep to avoid drowsiness or decreased concentration the next day. Patients should not take the medication immediately after waking up in the middle of the night to avoid compromising safety. It is recommended to start with a low dose for the first time and gradually adjust to the optimal dose according to the efficacy.

Dalirasin is generally well tolerated, and common side effects include mild headache, drowsiness, or mild dizziness, which usually resolve spontaneously. During long-term use, simultaneous use with other central depressants (such as alcohol, sedatives) should be avoided to reduce the risk of excessive sedation. Patients should maintain a regular schedule and healthy living habits during use, and have regular follow-up visits to evaluate the efficacy and side effects. The scientific use of Dali Lasen can effectively extend sleep time, improve night awakening problems, and improve overall quality of life.

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