Correct usage and safety instructions for taking ensifentrine-Ohtuvayre

Ensifentrine (trade name Ohtuvayre) is a new inhaled dual phosphodiesterase (PDE3/PDE4) inhibitor, used for the treatment of chronic obstructive pulmonary disease (COPD). Correct usage and scientific taking procedures are crucial to ensuring drug efficacy and reducing the risk of adverse reactions. This article will explain in detail the four aspects of medication use, operating procedures, precautions and safety guidance.

First of all, ensefentin is an inhaled preparation, and patients should use a dedicated spray inhaler for administration. Before use, you should read the drug instructions carefully and confirm the drug dosage. It is generally recommended to inhale 3mg/2.5mL (60 doses) each time, and follow the doctor’s prescription for daily dosage. The inhaler needs to be shaken well before use to ensure even distribution of the medicinal solution and to avoid uneven dosage leading to reduced efficacy.

Secondly, the medication process needs to be strictly followed. Patients should clean their mouth first to avoid drug residue in the mouth or throat during inhalation. When using the inhaler, you should put the medicine nozzle into your mouth, take a deep breath and press the inhaler at the same time to allow the medicine to enter the lungs evenly. After inhalation, you should hold your breath for about 5 to 10 seconds, and then exhale slowly to ensure that the drug is fully deposited in the bronchus and alveoli. After each inhalation, it is recommended to rinse your mouth with water to reduce mouth and throat discomfort and potential drug irritation.

Thirdly, patients should pay attention to keeping the inhaler clean during use. They should wipe the nozzle with a clean cloth or paper towel after daily use, and regularly disassemble and wash the parts of the inhaler according to the instructions to prevent bacterial growth. If cough, throat irritation or mild shortness of breath occurs during use, the medication can be suspended and the symptoms should be observed. If symptoms persist or worsen, contact your doctor immediately.

Finally, in terms of safety guidance, exefantine should not be mixed with other respiratory drugs without medical guidance. Patients should inhale regularly according to the dosage and frequency instructed by the doctor, and should not increase or decrease the dosage on their own. For patients with severe cardiovascular disease, liver and kidney dysfunction, or allergies to the ingredients of this product, they should be used with caution under the guidance of a doctor. During long-term use, lung function should be reviewed regularly to evaluate efficacy and tolerance to ensure medication safety and maximum therapeutic effect.

Reference materials:https://www.drugs.com/