How much does a box of Dasatinib cost?

Dasatinib (Dasatinib) is a broad-spectrum tyrosine kinase inhibitor (TKI) developed by Bristol-Myers Squibb in the United States. The trade name is Sprycel (Chinese name: Shidasai). It is mainly used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). As a BCR-ABL inhibitor, dasatinib can inhibit multiple signaling pathways at the same time, including BCR-ABL, SRC family kinases, KIT, PDGFR, etc., providing a new treatment option for patients who are resistant or intolerant to imatinib.

In China, dasatinib has officially obtained marketing authorization and been included in the national medical insurance directory. Its medical insurance reimbursement scope is mainly limited to patient groups that meet specific conditions. The implementation of the medical insurance policy has greatly reduced patients' medication burden and significantly improved the accessibility of this high-priced targeted drug. Common specifications include two packaging forms: 50mg×60 tablets and 20mg×60 tablets. According to current data from domestic pharmacies and online drug supply platforms, the price of the original drug dasatinib is approximately RMB 10,000. The specific price varies slightly depending on regions and sales channels.

In comparison, the original Sprycel price in overseas marketsis much higher. In European and American countries, the price of a box of dasatinib (100 mg, 30 tablets) usually exceeds US$10,000, making it a high-priced patented drug. With the expiration of patents and the launch of generic drugs, countries such as India and Bangladesh have launched generic versions of dasatinib with the same ingredients and dosage as the original drug. These generic drugs have passed quality certification in many countries, and their bioequivalence is close to that of the original drugs, while the price is only a few tenths of that of the original drugs. In some overseas pharmacies or cross-border channels, the price of dasatinib generics ranges from a few hundred to one thousand yuan, depending on the brand, specifications and exchange rate fluctuations.

Reference materials:https://go.drugbank.com/drugs/DB01254