A summary of Axitinib (Inlida) side effects and countermeasures to help patients reduce medication discomfort

Axitinib (Axitinib) is an oral tyrosine kinase inhibitor mainly used for the treatment of advanced or metastatic renal cell carcinoma. Although its targeting effect is significant, some side effects may still occur during clinical use. Common adverse reactions include hypertension, fatigue, diarrhea, thyroid dysfunction, decreased appetite, and hand-foot syndrome. Although most of these side effects are mild to moderate, if not treated in time, they may affect the patient's quality of life and treatment compliance.

For hypertension, axitinib can cause an increase in blood pressure, and patients should assess their blood pressure levels before taking the drug and monitor them regularly during treatment. When blood pressure rises, you can use antihypertensive drugs to control it under the guidance of a doctor, and adjust your lifestyle, such as a low-salt diet, moderate exercise and adequate sleep, to reduce the adverse effects of the drugs.

Fatigue, decreased appetite, and gastrointestinal discomfort are also common side effects. Patients can relieve fatigue and loss of appetite through regular work and rest, moderate exercise, small and frequent meals, and balanced nutrition. In case of diarrhea, water and electrolytes should be replenished, and antidiarrheal drugs can be used under the guidance of a doctor if necessary. For hand-foot syndrome, long-term friction should be avoided, comfortable shoes and socks should be used, and moisturizing or soothing ointments can be applied externally to reduce skin discomfort.

In addition, axitinib may affect liver function and thyroid function, so liver function, kidney function and thyroid indicators should be checked regularly during treatment. If obvious abnormalities occur, the doctor should be informed promptly so that the dose can be adjusted or the medication can be temporarily discontinued. Overall, through regular monitoring, reasonable life intervention and drug management under the guidance of a doctor, most side effects can be effectively controlled, thereby helping patients maintain treatment effects while minimizing discomfort.

Reference materials:https://www.drugs.com/