Is guselkumab suitable for long-term maintenance treatment?

Guselkumab is suitable for long-term maintenance treatment of patients with moderate to severe psoriasis or psoriatic arthritis, with the goal of maintaining disease remission and reducing rash recurrence and joint damage. Clinical data shows that continuous use can maintain the efficacy of PASI 90 for more than 2 years, while the patient's quality of life is significantly improved. During long-term treatment, infection risk, blood routine and liver function indicators need to be regularly monitored, and the dose or injection interval should be adjusted according to the patient's efficacy and tolerance. Individualized management and dynamic assessment are the keys to ensuring long-term efficacy and safety. Reasonable long-term maintenance treatment can significantly delay disease progression.