Is clofazimine a second-line drug?

Clofazimine is indeed a second-line drug. In anti-tuberculosis treatment, drugs are usually divided into first-line and second-line drugs. First-line drugs, such as isoniazid and rifampin, have good efficacy and few adverse reactions. Second-line drugs, including clofazimine, are mainly used as alternative treatments when first-line drugs are resistant or patients cannot tolerate the side effects of first-line drugs. Clofazimine is not only effective against Mycobacterium tuberculosis, but also against other mycobacteria such as Mycobacterium leprae. However, it should be noted that its use should be based on medical advice, and the dosage and use time should be strictly controlled to reduce adverse reactions. Therefore, clofazimine plays a key role as an important second-line drug in anti-tuberculosis and anti-leprosy treatment.