What are the limitations or contraindications for the use of Platinib?

Pralsetinib (Pralsetinib), as a kinase inhibitor, has some limitations and contraindications for its use. If the patient has an allergic reaction to Platinib or its ingredients, its use should be strictly prohibited to avoid severe allergic reactions. Because platinib may cause harm to the fetus, pregnant women should not take this drug. At the same time, lactating women should also use it with caution to avoid passing the drug to the baby through breast milk. In addition, the use of platinib is also restricted by some specific disease states, such as patients with severe renal impairment, moderate or severe liver impairment, etc. It should be used with caution. It also needs to be used with caution in patients with interstitial lung disease or pneumonia and to pay close attention to pulmonary symptoms.