What are the common adverse reactions of Platinib?

In clinical studies, the most common adverse reactions (≥25%) of pralsetinib (Pralsetinib) were musculoskeletal pain, constipation, hypertension, diarrhea, fatigue, edema, pyrexia, and cough. The most common grade 3-4 laboratory abnormalities (≥2%) were lymphopenia, neutropenia, decreased hemoglobin, decreased phosphate, leukopenia, decreased sodium, increased aspartate aminotransferase (AST), increased alanine aminotransferase (ALT), decreased calcium, thrombocytopenia, increased alkaline phosphatase, increased potassium, decreased potassium, and increased bilirubin. If a patient experiences side effects after using Platinib, it is recommended to adjust the drug dosage under the guidance of a doctor.