Which drugs cannot be used with serputinib/serpatinib at the same time?

Selpercatinib/Selpercatinib cannot be used with certain drugs. If you need to use a proton pump inhibitor while taking seputinib, it is best to take it orally with food to avoid drug interactions; if it is unavoidable to use histamine H2 receptor blockers at the same time, it is recommended to take the drug 2 hours before or 10 hours after taking it; similarly, if it cannot be avoided with the drug that neutralizes gastric acid, it is recommended to take the drug 2 hours before or 2 hours after taking it. If you do need to use these drugs together, it is best to consult your doctor to ensure that drug interactions are properly managed.