购买一盒雷帕鸣(西罗莫司片)要花多少钱

(Sirolimus tablets) is a new, powerful, low-toxic macrolide immunosuppressive drug. It is mainly used clinically to prevent rejection of kidney transplants. It does not inhibit calcineurin after binding to cytoplasmic proteins, so it can completely avoid the nephrotoxicity of calcineurin inhibitors (CNI). It is one of the best choices when liver or renal insufficiency occurs after organ transplantation or when CNI cannot reach the ideal drug concentration.

Rapamin inhibits the activation and proliferation of T lymphocytes stimulated by antigens and cytokines (interleukins IL-2, IL-4 and IL-15). It also inhibits the production of antibodies. In cells, rapamycin binds to the immunophilin, FK-binding protein-12 (FKBP-12), to generate the FKBP-12 immunosuppressive complex. This complex binds to the mammalian sirolimus BA molecule (mTOR, a key regulatory kinase) and inhibits its activity, thereby inhibiting the progression from the G1 phase to the S phase in the cell cycle.

In clinical trials, rapamin (sirolimus tablets) was used in kidney transplant patients, which not only effectively reduced the risk of rejection, but was also relatively safe. Some studies have also found that the use of rapamycin can reduce the incidence of skin cancer after kidney transplantation, providing a new option for postoperative prevention in kidney transplant patients.

The effect of Leipaming is obvious, so how much does it cost to buy a box?

It is understood that the price of sirolimus tablets produced by Biocon Pharmaceutical Factory in India is relatively low. The specifications are 1mgx10 tablets and the price is around 200$. Patients can go abroad to buy it at regular pharmacies in India. If it is inconvenient to go abroad, they can also consult the Medical Companions Overseas Medical Consulting Service Company to learn about the formal purchase method.

Recommended related hot articles: /newsDetail/82574.html