吃雷帕鸣(西罗莫司片)效果怎么样

(Sirolimus tablets), brand name Rapamune, is suitable for patients aged 13 or above who have received kidney transplants to prevent organ rejection. Recommended for use in combination with cyclosporine and corticosteroids. For patients who receive a kidney transplant, rejection after surgery is what everyone is most worried about. This may mean that the surgical treatment fails and the patient cannot survive long-term. The use of Rapamin can effectively reduce the failure rate after transplantation.

What are the effects of taking Rapamin (sirolimus tablets)?

Rapamin combined with low-dose cyclosporine A is a better immunosuppressive treatment option after renal transplantation, and the use of rapamin (sirolimus tablets) can reduce the dose of CNI. After renal transplantation, it is safe and effective to control the steady-state trough concentration of rapamycin at 4-8ng/ml or 5-8ng/ml. Rapamin also reduces the incidence of non-melanoma skin cancer after kidney transplantation. In addition, rapamycin has also achieved good anti-rejection effects after heart transplantation, lung transplantation, corneal transplantation and other transplants, but the therapeutic concentration has not been reported.

It can be seen that the use of rapamycin (sirolimus tablets) in kidney transplant patients can not only effectively reduce the risk of rejection, but is also relatively safe. However, immunosuppression may also increase the risk of infection, including activation of underlying viral infections (including BK virus-related nephropathy), fatal infections, and sepsis. Patients need to take relevant precautions, including preventive treatment of Pneumocystis jiroveci pneumonia (PCP) 1 year after transplantation, and prevention of cytomegalovirus (CMV) 3 months after transplantation.

The above is an introduction to the therapeutic effects of sirolimus tablets. If you are allergic to rapamycin or any component of the preparation, you should not use this product. Please follow your doctor's advice during treatment.

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