有心脏病可否服雷帕鸣西罗莫司片

The approved indication is to treat kidney transplant patients and prevent organ rejection in patients 13 years of age or older. Recommended for use in combination with cyclosporine and corticosteroids. As early as 1989, Morris officially began to study Rapamin and Sirolimus Tablets as a new highly effective immunosuppressant for the anti-rejection effect of organ transplantation. The results showed that Rapamin and Sirolimus Tablets' effective anti-proliferative effect on peripheral blood mononuclear cells was 50 to 500 times stronger than that of cyclosporine CA, but its nephrotoxicity was lower than that of cyclosporine and tacrolimus.

The recommended way of taking rapamycin (sirolimus tablets, sirolimus) is: orally, once a day. It should be started as soon as possible after transplantation. For new transplant recipients, the loading dose that should be taken for the first time is three times the maintenance dose. The recommended loading dose of rapamin sirolimus tablets for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day.

Although the loading dose of 15 mg and the maintenance dose of 5 mg/day used in clinical trials are safe and effective, the therapeutic benefits of doses above 2 mg are unclear for kidney transplant patients. The overall safety profile of patients taking 2 mg of rapamin and sirolimus tablets daily is better than that of patients taking 5 mg of rapamin and sirolimus tablets daily.

Can patients with heart disease take rapamycin sirolimus tablets?

According to the drug instructions of rapamin (sirolimus tablets), patients who are currently allergic to rapamin sirolimus tablets, derivatives of rapamin sirolimus tablets, or any ingredients in the oral solution of this drug, pregnant women and lactating women should not take rapamin sirolimus tablets to avoid posing a certain threat to their own safety. Although there are no certain restrictions on patients with heart disease in the instructions for rapamin sirolimus tablets, for the sake of your health, it is recommended to take it under the guidance of a physician.

The therapeutic effect is remarkable, but treatment with rapamin sirolimus tablets will also produce certain side effects or adverse reactions, including: peripheral edema/hypertension/edema/chest pain/deep vein thrombosis/pulmonary embolism/headache/pain/dizziness/acne vulgaris/hypertriglyceridemia/diabetes/ovarian cyst/constipation/diarrhea/stomatitis, etc.

Recommended related hot articles: /newsDetail/82419.html