雷帕鸣(西罗莫司片)怎么吃效果好

In September 1999, it was approved by the US FDA and officially launched on the market. Sirolimus (sirolimus tablets) is mainly used to prevent and treat rejection of kidney, liver and other transplants, especially for patients with renal dysfunction, tremor and hypertension. Rapamin (sirolimus tablets) has low oral bioavailability, large inter-individual pharmacokinetic (PK) differences, and is a substrate of CYP3A and P glycoprotein (PgP), which can cause drug-drug interactions with a variety of drugs. 

  When patients who take calcineurin inhibitor drugs after kidney transplantation develop chronic allograft nephropathy, using rapamycin (sirolimus tablets, sirolimus) instead of calcineurin inhibitor drugs can improve renal function to a certain extent. 

How to take Rapamin (sirolimus tablets) for best results?

In order to achieve good therapeutic effects during the actual treatment of patients with rapamin (sirolimus tablets), it is clinically recommended to use rapamin (sirolimus tablets, sirolimus) in combination with cyclosporine and corticosteroids, which can be taken orally once a day, regularly with or without food. Since the bioavailability of crushed, chewed, or cut tablets has not been established, patients are advised to swallow the tablets whole during administration.

Rapamin (sirolimus), a macrolide compound, is a potentially new and potent immunosuppressant with less toxicity discovered so far, providing a new treatment alternative for transplant recipients. Patients need to follow the doctor's instructions carefully and use the medicine in the correct way during the treatment process.

Taking it for treatment may cause hyperlipidemia, which may increase blood lipids (cholesterol and triglycerides). Patients with hyperlipidemia should use this drug with caution. Patients should monitor cholesterol/lipids while receiving sirolimus; if hyperlipidemia occurs, follow current management guidelines (diet, exercise, lipid-lowering agents). Antihyperlipidemic treatments may not be effective in achieving normal levels.

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