司帕生坦不同版本一盒的最新价格公布

Sparsentan is an innovative drug used to treat primary immunoglobulin A nephropathy and can effectively reduce proteinuria levels. Since the drug is not yet available in China, patients need to purchase different versions through overseas channels. This article will introduce in detail the latest prices, clinical efficacy and possible side effects of various versions of sparsentan to help patients better understand this drug.

The latest prices for a box of different versions of Sparsentan

Currently, there are two versions: original drug and generic version, with large price differences. Below is specific pricing information for each version.

Price of the original drug in the United States

The original drug is produced by Travere Therapeutic Company in the United States. The specification is 400mg*30 tablets/box, and the reference price is about US$15,277. This version is suitable for patients with better financial conditions, but the price is higher.

Prices of generic drugs in Laos

The specifications of generic drugs produced by Lucius in Laos are 400mg*30 tablets/box, and the reference price is about US$1,073. Generic drugs are relatively less expensive and more suitable for patients with limited budgets.

When choosing medicines, patients need to choose the most suitable version based on their own financial conditions and treatment needs.

Efficacy of Sparsentan

Sparsentan is a dual endothelin and angiotensin receptor antagonist. Clinical studies have shown that it has significant efficacy in patients with IgAN.

Reduce proteinuria

Sparsentan can effectively reduce the urine protein to creatinine ratio (UPCR) and is suitable for IgAN patients with UPCR ≥ 1.5g/g. Clinical trials have shown that the drug can significantly reduce proteinuria levels and delay disease progression.

Delay the deterioration of renal function

By inhibiting ETAR and AT1R targets, sparsentan can reduce glomerular damage, protect renal function, and reduce the risk of end-stage renal disease.

The efficacy of sparsentan varies between individuals, and patients need to develop a personalized treatment plan under the guidance of a doctor.

Sparsentan’s side effects

Although Sparsentan is effective, it may also cause some side effects, and patients need to pay close attention to it.

Common side effects

The most common adverse reactions include peripheral edema, hypotension, dizziness, hyperkalemia and anemia, with an incidence rate of ≥5%. Patients need to regularly monitor blood pressure and potassium levels during medication.

Serious side effects

Sparsentan may cause serious side effects such as liver toxicity, embryo-fetal toxicity, and acute kidney injury. Liver function tests are required before use. Pregnant women are contraindicated. Women of childbearing age need to take contraceptive measures.

If patients experience discomfort during medication, they should seek medical treatment promptly and adjust the treatment plan.