斯帕森坦一次能囤几盒?多少钱?

Sparsentan is a new drug used to treat primary immunoglobulin A nephropathy (IgAN), which has attracted attention due to its unique dual antagonistic mechanism. This article will focus on the three core issues that patients are most concerned about: single purchase quantity limits, drug pricing, and medication precautions for special groups, providing readers with practical reference information.

How many boxes of Sparsentan can be stored at a time

For kidney disease patients who require long-term medication, the amount of drug reserves directly affects the continuity of treatment. As a prescription drug, its purchase quantity is restricted by many factors.

U.S. market purchase regulations

In the United States, where the original drug is launched, most pharmacies implement a 30-day prescription volume management policy. According to the official recommended dose of Travere Therapeutics (400mg per day), the standard packaging of 30 tablets/box covers exactly one month of treatment, and patients can usually purchase up to 3 boxes (90-day supply) at a time.

Restrictions on cross-border drug purchases

When purchasing via international express delivery, China Customs has clear quantity limits on medicines for personal use. A single mailing of more than 3 months’ worth (approximately 3 boxes) may be considered commercial use, and additional supporting materials are required.

A reasonable reserve of 3 months' dosage can not only meet the treatment needs, but also comply with the drug circulation management regulations of various countries.

How much does Sparsentan cost?

The pricing of Sparsentan reflects its research and development costs and patent value, and patients need to make financial planning in advance.

Official pricing system

The price announced by the American company Travere Therapeutics is US$15,348 per box (400mgx30 tablets). Based on the recommended dosage, the annual treatment cost is approximately US$184,000, excluding insurance discounts.

Actual payment cost

Patients in areas not covered by medical insurance must pay the full amount out of pocket. Cross-border purchases also require about 15%-20% of cold chain transportation fees, tariffs and service fees.

High drug prices require most patients to formulate long-term drug budgets or seek support from charitable assistance projects.

Sparsentan medication for special groups

There are additional risks when using sparsentan for people with specific physiological conditions, and the principle of individualized medication must be strictly followed.

Contraindicated for women of childbearing age

The drug instructions clearly indicate that it is contraindicated during pregnancy. A pregnancy test must be performed before taking the drug, and highly effective contraceptive measures must be taken during treatment and 1 month after stopping the drug.

Patients with abnormal liver function

It is contraindicated in patients with Child-Pugh classification B/C. Transaminases need to be tested before treatment, and liver function should be monitored monthly during treatment. Clinical data show that 3.5% of patients have ALT/AST ≥ 3 times the upper limit of normal values, and need to stop taking the drug immediately.

Elderly patients (≥65 years old) and those with mild renal impairment (eGFR≥30) do not need to adjust the dose, but it is recommended to strengthen blood pressure and serum potassium monitoring.