氨己烯酸片(喜保宁)多久有效果

Also known as Vigabatrin, it was approved for marketing in the United States in August 2009. It can be used as an auxiliary treatment for anti-epilepsy, auxiliary treatment of partial seizures of refractory complex epilepsy, and can also be used to treat infantile spasms and Lennox-Gastaut syndrome, and for tardive dyskinesia.

In terms of usage and dosage, the initial dose of vigabatrin tablets for the treatment of infantile spasms (1 month to 2 years old) is 50 mg/kg/day, taken orally, in two divided doses, and can be taken with or without food. The dose may be increased in increments of 25 to 50 mg/kg/day every 3 days, up to a maximum of 150 mg/kg/day. The maximum daily dosage for adults is 2-3g. It is appropriate to start with 1g a day. Then, depending on the response after taking the medication, if the response is good, it can be increased by 0.5g every week, and finally reaches a dosage of 2-3g per day.

In foreign literature, the therapeutic dose of vigabatrin tablets (Vigabatrin) is 0.10 to 0.15g/(kg·d), which generally takes effect 2 weeks after the initial treatment, manifested by the reduction or disappearance of convulsive attacks and the disappearance of peak arrhythmia-like EEG. Patients need to follow the doctor's instructions carefully while taking the medication and do relevant examinations.

The main component of vigabatrin tablets (vigabatrin) is vigabatrin (vigabatrin). Its mechanism of action is to irreversibly inhibit GABA aminotransferase (GABA-T) and increase the concentration of GABA in the brain. In the past two years, more and more children with TSC have effectively controlled epilepsy by using vigabatrin tablets. Western countries even use vigabatrin tablets to prevent brain abnormalities in children with TSC who have not yet developed the disease. This shows that it has a positive effect on the treatment of epilepsy.

The above is an introduction to the effects of (Vigabatrin), I hope it will be helpful to you.

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