The correct way to purchase larotrectinib

Larotrectinib (trade name Vitrakvi), as an innovative and highly selective tropomyosin receptor kinase (TRK) inhibitor, has brought new treatment hope to patients with TRK fusion-positive solid tumors since its approval in the United States. However, due to the higher prices of their original drugs, the emergence of generic drugs has provided more patients with affordable treatment options. This article will briefly introduce the correct way to purchase larotrectinib generics and discuss how to deal with hypocalcemia during treatment.

How to purchase larotrectinib generics

Hospital pharmacies and pharmacy consultation: In some countries and regions, generics may have entered hospital pharmacies or retail pharmacies through formal channels. Patients can contact their local hospital or pharmacy to learn about drug availability and purchasing procedures. When purchasing, be sure to present a doctor's prescription to ensure legal compliance.

Online purchase: With the development of the Internet, some legitimate online pharmacies or drug distributors also provide online purchase services for larotrectinib generics. When patients choose to purchase online, they should ensure that the website is reputable, legal and compliant, follow the website's purchasing guidelines to complete the purchase process, and pay attention to checking drug information to ensure that they are purchasing genuine drugs.

Treatment of hypocalcemia

During larotrectinib treatment, some patients may experience hypocalcemia as an adverse reaction. Treatment for hypocalcemia mainly includes the following aspects:

Calcium supplementation: For patients with mild to moderate hypocalcemia, calcium supplementation can be administered orally or intravenously. Oral calcium agents such as calcium carbonate, calcium citrate, etc. must be taken according to the dosage prescribed by your doctor to avoid overdose. When calcium is supplemented through the intravenous route, it must be performed by professional medical staff in the hospital to ensure safety.

Supplement vitamin D: Vitamin D helps promote the absorption and utilization of calcium and plays an important role in preventing and treating hypocalcemia. Patients can supplement vitamin D preparations, such as vitamin D3, in appropriate amounts under the guidance of a doctor.

Adjust the dose of larotinib: If hypocalcemia is caused by larotinib and the symptoms are severe or persistent, the doctor may consider adjusting the dose of larotinib or temporarily discontinuing the drug. Patients should consult their doctor before adjusting the dosage or discontinuing the medication and avoid adjusting the dosage or discontinuing the medication on their own.

Monitor blood calcium levels: During treatment, patients should regularly monitor blood calcium levels in order to promptly detect and deal with adverse reactions such as hypocalcemia. The doctor will develop a personalized monitoring plan based on the patient's specific situation to ensure that the treatment is safe and effective.