Larotrectinib price list

In the vast field of anti-tumor drugs, larotrectinib, as an innovative therapy, has brought hope to many patients with its precise therapeutic effect on specific genetic mutations. However, there are significant differences in the prices of larotrectinib from different sources (original drug and generic drug), which is an important factor that cannot be ignored for patients and their families when choosing treatment options.

Original drug price overview

capsules produced by Bayer in Germany have won wide recognition in the market with their rigorous manufacturing process and strict quality control. It provides two specifications - 25 mg 56 tablets and 100 mg 56 tablets, respectively, to meet the treatment needs of different patients. A box of 25mg is priced at $15,340, while a box of 100mg is as high as $52,000, which is undoubtedly a considerable financial burden for patients undergoing long-term treatment.

In order to adapt to the medication habits of more patients, Bayer of Germany has also launched larotrectinib oral solution, with a specification of 20mg/ml and a price of 18,228$ per box. This dosage form provides patients with a more flexible way of taking medication.

Price advantage of generic drugs

Bangladesh Everest and Yaopin International Bangladesh Everest and Yaopin International have both launched generic drugs of larotrectinib in 100mg*30 capsules, priced at 4520$ and 4000$ respectively. Compared with the original drug, the price advantage is significant, providing more patients with affordable treatment options.

Laos Lucius: As another manufacturer that provides larotrectinib generics, Laos Lucius’s product is priced at 1,950$ per box (100mg*30 tablets), further reducing the financial pressure on patients.

Recommended Dosage Guidelines for Larotrectinib

Adult and pediatric patients with a body surface area of ​​at least 1.0 m²: For these patients, the recommended dose of Larotrectinib is 100 mg orally administered twice daily. Whether taken with food or not, good therapeutic effects can be achieved. This dose setting is designed to effectively control disease progression while minimizing the occurrence of adverse reactions.

Pediatric patients with body surface area <1.0m²: For pediatric patients with small body surface area, the dose of larotrectinib needs to be adjusted according to the body surface area. The recommended dose is 100 mg/m² twice daily. This personalized dosing ensures the safety and effectiveness of the treatment and helps achieve optimal therapeutic results.

Larotinib, as a model of precision medicine, has a sharp contrast in price between its original drug and generic drugs, providing patients with a variety of treatment options. Formulating a reasonable dosage based on the patient's specific conditions (such as age, body surface area, etc.) is the key to maximizing the therapeutic effect. When choosing a treatment plan, patients and their families should consider various factors such as financial affordability, treatment efficacy, and safety to make the decision that is most suitable for them.