How many specifications does evantumumab have? How much does it cost?_ Kanghule

is a bispecific antibody that recognizes the epidermal growth factor receptor (EGFR) and the MET proto-oncogene (MET). In May 2021, the Food and Drug Administration granted accelerated approval to evantumumab for the treatment of patients with non-small cell lung cancer (NSCLC) with EGFR exon 20 insertions (Exon20ins) that have progressed after platinum-based chemotherapy. As of now, there is only one specification of evantumumab, with a box of 350mg/7ml priced at around $10,300.

Specifications and price of evantumumab

Regarding the specifications of evantumumab, according to the instructions issued by Johnson & Johnson, the specification of the drug is a single-dose bottle, each bottle containing 350mg/7mL (50mg/mL) solution.

1. Drug price: As an innovative drug, the price of evantumumab is relatively high. The specific price varies depending on factors such as region, hospital, and drug specifications. In China, evantumumab has not yet been officially launched, so there is no official domestic pricing. However, according to information from some overseas drug purchasing channels, the price of 350 mg evantumumab from Janssen Pharmaceuticals in the United States is approximately $10,300. It should be noted that these prices are for reference only and may change due to exchange rates and other factors during actual purchase.

2. Drug specifications: Evantumumab (trade name: Rybrevant, generic name: amivantamab) is an EGFR/MET bispecific monoclonal antibody developed by Janssen Pharmaceuticals. It is mainly used to treat specific types of non-small cell lung cancer. The strength of this drug is 350mg/7ml, which means each ml contains 50mg of amivantamab. This specification of evantumumab is designed to meet the precise control of drug dosage in clinical treatment. Recommended dosage will vary based on patient weight. For example, patients weighing less than 80 kg receive a dose of 1050 mg, while patients weighing 80 kg and above receive a dose of 1400 mg. This dosage setting helps ensure the efficacy of the drug while reducing the risk of adverse reactions.

Warm reminder: After purchasing evantumumab, there are strict requirements for the storage conditions of the drug. It needs to be refrigerated at 2-8°C to ensure the stability and effectiveness of the drug. During clinical use, patients should strictly follow the doctor's instructions. The doctor will formulate a personalized treatment plan based on the patient's specific situation and closely monitor the patient's response and the safety of the drug.