Interpret the general instructions on how to purchase and take adagrasib

Introduction: Adagrasib is a drug for the treatment of lung cancer. It is mainly used to treat adult patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with KRAS G12C mutations. Adagrasiib is an irreversible inhibitor of the RAS GTPase family and blocks the growth and spread of tumor cells by inhibiting the function of KRAS G12C protein. This article mainly talks about the purchase method, dosage guide, treatment of vomiting and missed doses, dosage adjustment and medication contraindications of adagrasiib for reference.

Purchase method

Adagrasib is a prescription drug, so it needs to be purchased under the guidance of a doctor. With a prescription, patients can go to regular hospital pharmacies, chain pharmacies or designated sellers to purchase adagrasib. In some areas, adagrasib can be purchased through online pharmacies. Choose a reliable online pharmacy and make sure it operates legally and has the right licenses. Patients can also obtain it through the help of domestic professional overseas medical service institutions, which are guaranteed to be authentic. For more details, please consult customer service staff.

Dosing Guide

The recommended dose of adagrasiib is 600 mg orally twice daily until disease progression or unacceptable toxicity occurs. Adagrasibu should be taken at the same time every day, before or after meals. Swallow the tablets whole without chewing, crushing or splitting the tablets.

Management of vomiting and missed doses

If vomiting occurs after taking adagrasib, do not take additional doses. If a dose is inadvertently missed and it is more than 4 hours before the intended administration time, the dose should be skipped and the dose should be resumed at the next scheduled time.

Dose adjustment

Dose adjustment may be necessary if adverse reactions occur. A maximum of two dose reductions are allowed. In patients who cannot tolerate 600 mg once daily, use of should be permanently discontinued. The specific dosage and regimen should be determined based on the patient's specific condition and the doctor's recommendations.

Drug contraindications

Adagrasib may have adverse effects on the fetus, so pregnant women should avoid using this drug. Breastfeeding women should also avoid use because the drug may be passed to the baby through breast milk. Patients with severe liver disease may need to have their dose adjusted or avoid this drug. If patients are allergic to adagrasib or its components, they may experience a severe allergic reaction and should discontinue use immediately and seek medical attention.

Adagrasib is not suitable for all patients with lung cancer, especially pregnant and lactating women, patients with severe liver disease, and patients who are allergic to adagrasib or its components should avoid use. Before taking adagrasib, patients should give their doctor details about other medications they are taking, including prescription drugs, over-the-counter drugs, and supplements, to avoid drug interactions.