Improvement measures for leg and foot edema caused by platinib

Introduction: Leg and foot edema caused by platinib may be caused by adverse drug reactions. Leg and foot edema is one of the most commonly reported adverse events in patients treated with platinib, and is mostly mild, with peripheral edema accounting for the largest proportion. Patients who experience edema in their legs and feet can improve it through a series of measures, such as adjusting their lifestyle, to relieve lower limb discomfort as soon as possible.

Indications for Platinib

is a prescription medicine used to treat certain cancers caused by abnormal rearrangements during transfection (RET) genes, including adults with non-small cell lung cancer (NSCLC) that has spread, and adults and adults with advanced thyroid cancer or thyroid cancer that has spread 12 Children over 10 years of age who require oral or injectable medications (systemic treatment) and have received radioactive iodine therapy but it did not work or is no longer effective.

Causes of edema in legs and feet caused by Platinib

Platinib may affect the body's fluid balance, causing fluid to accumulate in body tissues, thereby causing edema, including peripheral edema, facial edema, periorbital edema, eyelid edema, generalized edema, swelling, etc. This side effect may be more obvious in some patients. If the patient takes other drugs at the same time, such as certain antihypertensive drugs, it may also cause or worsen the edema of the legs and feet. The median time to the first occurrence of edema was 42 days, and the median duration was 163 days. Among them, 5.8% and 6.1% of patients respectively suspended or reduced treatment due to edema.

Measures to improve edema in legs and feet

1. Adjust lifestyle: It is recommended that patients pay more attention to rest and elevate the affected limb. It is recommended to elevate the leg above the level of the heart every day for about 30 minutes each time. When sleeping at night, you can put a pillow on your ankle to help reduce swelling. You can also massage the swollen area to relieve symptoms. Patients with moderate to severe edema need to select and use elastic stockings under the guidance of a doctor.

2. Diet adjustment: Pay attention to a light diet and control sodium intake. It is better to reduce sodium intake to avoid aggravation of edema. At the same time, pay attention to monitoring your weight and regularly consult a nutritionist to make appropriate dietary adjustments.

Usage and Dosage

The recommended dose of Platinib is 400 mg, taken orally once a day, and Platinib needs to be taken on an empty stomach. Fasting is required at least 2 hours before and at least 1 hour after taking Platinib. It cannot be taken with food.

Price of generic platinib

Currently, it is understood that the reference price of Lucius’s generic platinib is approximately between 3715$-4000$, but the price of the drug will also change, and the actual price at the time of purchase should prevail.