Where to buy cabozantinib

Cabotinib is a targeted therapy drug mainly used for the treatment of renal cell carcinoma, hepatocellular carcinoma and thyroid cancer. Since this drug is expensive and requires long-term use, patients and their families need to know key information such as its purchasing channels, quantity of medicines to prepare, and the duration of medication. This article will introduce these three aspects in detail to help patients plan their treatment plan more rationally.

Purchasing channels for Cabozantinib

is a prescription drug, and its purchasing channels are strictly regulated, and patients need to obtain it through formal channels.

Purchase in hospital pharmacies

Cabozantinib is usually available in oncology departments or pharmacies of specialized hospitals in large domestic hospitals. Patients need to purchase it with a doctor's prescription and can use it under the guidance of a doctor.

Regular pharmacy channels

Some large chain pharmacies may provide cabozantinib. Before purchasing, please note that the pharmacy must have oncology drug business qualifications, and the drug traceability code should be checked when purchasing. Prices at pharmacies are usually the same as those at hospitals, and some offer delivery services.

Overseas drug purchase channels

For patients who need generic drugs, they can purchase Indian or Bangladeshi generic drugs through legal channels, such as overseas medical treatment, overseas drug purchase, etc.

The number of cabozantinib preparations

Rational preparation of drugs can not only ensure the continuity of treatment, but also avoid drug waste. It needs to be accurately calculated according to the treatment plan.

Basic preparation dosage calculation

Based on the standard dose of 60mg/day, 2 boxes of 30 pills are required per month. Taking into account possible dosage adjustments, it is recommended to prepare a 3-month supply of medicine for the first time, that is, 6 boxes. Patients with small body surface area will need 3 boxes of 40mg per month based on 40mg/day calculation.

Preparing medicines for special circumstances

For patients who need to go abroad or live in remote areas, it is recommended to prepare enough medicines for 6 months. At the same time, 1-2 boxes of emergency supplies need to be reserved to deal with emergencies such as logistics delays. Medications should be protected from light and stored below 25°C.

The course of cabozantinib treatment

Caboozantinib requires long-term continuous medication, and the specific course of treatment is individually adjusted based on efficacy and tolerance.

Standard medication cycle

The basic treatment plan is to continue taking it once a day until disease progression or intolerable toxicity occurs. Clinical data shows that the median medication time is about 7-14 months, and some patients with good response can be treated for more than 2 years.

Efficacy evaluation node

The first efficacy evaluation will be conducted at 8-12 weeks after treatment, and tumor changes will be examined through CT/MRI. Patients who are stable or shrinking should continue taking medication and be reviewed every 8-12 weeks. Medication should be suspended if grade 3 or above toxicity occurs.

Dose adjustment plan

Common adjustments include: first reduction to 40mg/day, and second reduction to 20mg/day. For patients under 60kg or elderly patients, start with 40mg/day. An interval of at least 2 weeks is required between each adjustment to ensure adequate observation.

Blood pressure, urinary protein and thyroid function need to be monitored regularly during the medication. Checks should be done every two weeks for the first two months, and then monthly. When hand-foot syndrome occurs, vitamin B6 can be used to relieve symptoms.