What are the purchasing channels for imfinzi?

Durvalumab was developed by the British company AstraZeneca. It is a PD-L1 inhibitor in clinical practice and is used to treat various malignant tumors such as non-small cell lung cancer and small cell lung cancer. It needs to be purchased with a prescription.

What are the purchase channels for Imfinzi?

Imfinzi has been launched in China. Patients can consider the following purchase methods:

Hospital pharmacies

Patients can purchase Imfinzi through pharmacies in large hospitals. You need to bring the prescription issued by the doctor, and the pharmacist will review it before picking up the medicine. The source of drugs in hospital channels is clear, and the production batch number and expiration date can be directly verified to avoid the risk of counterfeiting.

Online drug purchase platform

Regular online medical platforms support the purchase of prescription drugs. Patients need to upload electronic prescriptions. Online drug purchase must verify platform compliance and confirm that the drug packaging is intact and comes with instructions. Some platforms provide medication consultation and price comparison services to help patients reduce the cost of purchasing medications.

After purchase, durvalumab needs to be stored in a refrigerator at 2°C to 8°C, avoiding light and freezing. If you find that the packaging is damaged or the medicine solution is turbid, you should contact the seller immediately for a return or exchange.

Usage and Dosage of Imfinzi

Strictly follow the doctor’s instructions when using Imfinzi. The following is an explanation of the dosage regimen and infusion process to help patients understand this drug.

Dose adjustment and indications

The dose of durvalumab needs to be adjusted according to the patient's weight and cancer type. For example, for patients with unresectable stage III non-small cell lung cancer who weigh ≥30kg, 1500mg should be intravenously infused every 4 weeks. When treating metastatic non-small cell lung cancer, tremelimumab and chemotherapy drugs need to be combined, once every 3 weeks. Please consult a professional doctor for the specific course of medication.

Preparation and infusion requirements

Durvalumab needs to be diluted with 0.9% sodium chloride or 5% glucose to a concentration of 1-15 mg/mL, and the infusion time is controlled within 60 minutes. The prepared medicinal solution can be stored under refrigerated conditions for 28 days and must be used within 8 hours at room temperature.

During treatment, blood routine, liver and kidney function and thyroid function need to be monitored regularly so that doctors can evaluate drug tolerance.

Precautions for the use of Imfinzi (Imfinzi)

Rational drug use needs to be based on individual circumstances. The following provides guidance from the aspects of special groups and adverse reactions.

Drug Restrictions for Special Populations

Durvalumab is contraindicated in pregnant women because animal experiments show that the drug components of durvalumab may cause fetal abnormalities. Breastfeeding women need to stop taking the drug for 3 months before resuming breastfeeding. Children's medication needs to be strictly evaluated for risks. Elderly patients do not need to adjust the dose, but liver function monitoring needs to be strengthened. Patients with mild to moderate hepatic and renal insufficiency usually do not need to reduce the dose, and severe patients should use it with caution.

Management of common adverse reactions

Patients with non-small cell lung cancer may experience anemia, fatigue or neutropenia, while patients with biliary tract cancer often experience nausea, constipation or rash. Mild symptoms can be relieved by dietary changes or short-term rest. If adverse reactions of grade 3 or above occur, you need to receive symptomatic treatment as directed by your doctor.

In daily care, patients should maintain a balanced diet, avoid raw and cold foods, and conduct appropriate walking or breathing exercises to enhance their physical fitness. The living environment needs to be kept clean and ventilated to reduce the risk of infection.