那他霉素滴眼液的功效与作用及副作用？

Natamycin eye drops are an antifungal drug mainly used to treat fungal blepharitis, conjunctivitis and keratitis caused by natamycin-sensitive microorganisms, including Fusarium solani keratitis.

Specifications

1. 5ml: 250mg.

2. 10ml: 500mg.

Efficacy and role

It is a tetraene polyene antibiotic with broad-spectrum antifungal activity and low toxicity. Natamycin eye drops have an antifungal effect and have a good therapeutic effect on blepharitis, conjunctivitis and keratitis caused by sensitive microorganisms such as Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium, including Fusarium solani keratitis.

Side effects

Mainly include allergic reactions, vision changes, eye discomfort, eye swelling, eye congestion, eye irritation, eye pain, foreign body sensation, abnormal sensation and tearing.

Treatment measures

1. Swollen eyes: It may be caused by an allergic reaction of local tissues to the drug or a mismatch between the osmotic pressure of the drug and the eye tissue. Generally, edema will subside naturally after stopping the medication. If edema is severe or lasts for a long time, stop taking the medicine immediately and consult a doctor.

2. Eye congestion: usually resolves on its own after stopping the medication.

3. Eye irritation, eye pain, foreign body sensation and abnormal sensation: It may be caused by local irritation caused by the instillation of drugs into the eyes. The drugs should be used correctly according to the doctor's instructions and avoid excessive instillation. If symptoms persist or worsen, the medication should be discontinued and a doctor should be consulted.

4. Tearing: Tearing may be a reflex reaction caused by drugs entering the eyes, which usually resolves on its own after stopping the drug.

Clinical Application

In an analysis of the application value of natamycin eye drops combined with itraconazole in the treatment of fungal keratitis, it was found that the therapeutic effect of natamycin eye drops combined with itraconazole on fungal keratitis is obvious.

Medication for special groups

1. Medication for pregnant and lactating women: Pregnant and lactating women should use it with caution.

2. Medication for children: The safety and effectiveness of natamycin eye drops for children are not yet completely clear, so it should be used with caution or not used.

Medication

1. Medication is limited to eye drops.

2. Apply natamycin eye drops to the epithelial ulcer or drop it into the fornix at the same time every day.

3. If the symptoms do not improve after 7-10 days of treatment with natamycin eye drops, it indicates that the infecting microorganism is not sensitive to natamycin, and whether to continue treatment should be decided based on the clinical re-examination results.

Price and version

1. Japanese version: The reference price of natamycin eye drops is about 350$ per box.

2. Indian version: The reference price of natamycin eye drops is about 99$ per box.

3. Medical insurance version: The winning bid price included in domestic medical insurance is about 798$, and the price after reimbursement will be cheaper than 798$.

Prevent the recurrence of dry eye syndrome

1. Develop good eye-use habits, ensure adequate sleep, avoid staying up late, and pay attention to the balance between work and rest when using eyes.

2. Regular review to prevent recurrence.

3. Apply hot compress to the eyeballs to promote oil secretion, keep the eyeballs moist, and relieve dry eyes.

4. Look less at electronic screens, look more into the distance, and pay attention to eyelid hygiene.

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