纳地美定的购买渠道

Introduction: Naldemedine is a selective peripheral μ-opioid receptor antagonist, mainly used to treat constipation caused by opioids without affecting the analgesic effect of the central nervous system. Since this drug is not yet available in China, many patients have questions about its purchase channels and precautions for use.

Purchase channels for Nadimedine

Currently, it cannot be purchased through conventional channels in China, and patients need to understand the legal ways to obtain it.

Purchase Channels

Patients can obtain Nadimedin through three main channels, including Japanese regular hospital pharmacies, international professional pharmacy purchase services, and cross-border medical service institutions. Japan's Shionogi Pharmaceutical's original drugs are available in major hospital pharmacies or physical pharmacies in Japan, and must be purchased with a prescription from a local doctor.

Purchase conditions

Purchasing Nadimedine requires a valid medical certificate and prescription. International pharmacies usually require patients to submit recent medical records and prescriptions from their original treating doctors. Some institutions provide remote consultation services to assist in obtaining electronic prescriptions.

Since the drug is not marketed in China, all purchase channels involve cross-border procurement, and patients should understand relevant customs regulations in advance.

Contraindications of naldimedine

Before using naldimedine, you must understand its contraindications to avoid serious adverse reactions.

Absolute contraindications

It is contraindicated in patients who are known to be allergic to naldimedine or any of its components. It is strictly prohibited in patients with gastrointestinal obstruction or suspected obstruction, as it may aggravate the condition.

Relative contraindications

Patients with severe renal impairment (eGFR<30) should use it with caution, and it is recommended that the dose be halved. Patients taking strong CYP3A4 inhibitors should avoid coadministration as the risk of adverse reactions may increase.

Before taking medication, you should inform your doctor in detail about your health status and medication history, and conduct a comprehensive evaluation.

How to store Nadimedine

The correct storage method is crucial to maintaining the effectiveness of the drug.

1. Storage conditions

Nadimedine should be stored in the original packaging and placed in a dry place away from direct sunlight. Ideal storage temperature is 20-25°C, short-term carrying is allowed at 15-30°C.

2. Expiration date management

Pay attention to the expiry date on the packaging. Expired drugs must be discarded. It is recommended to use it within 6 months after opening the bottle to avoid deterioration of the medicine due to moisture.

Nadimedine is a prescription drug and must be used under the guidance of a doctor and may not be shared or resold with others.