达利雷生(Quviviq)中文说明书

Author: Medicalhalo

Release time: 2025-10-19 11:44:20

The successful launch of a dual orexin receptor antagonist developed by the Swiss company Idorsia has brought a new treatment option to domestic insomnia patients. The treatment of some insomnia patients, especially middle-aged and elderly insomnia patients, will greatly reduce the long-term dependence and relative safety of drug dependence.

Quviviq ‌Indications‌

It is used for adult patients who have difficulty falling asleep or maintaining sleep.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Usage and dosage of Quviviq

1. How to use Quviviq

Take it once every night 30 minutes before going to bed. Avoid taking it with meals (it may delay the onset of effect). You must ensure at least 7 hours of sleep after taking the medicine.

Based on the patient’s medical condition, if no significant improvement is seen within 7-10 days, a follow-up visit should be made in time to make reasonable adjustments for further treatment.

2. Quviviq dosage information

‌Standard dose‌: 25-50mg/night (maximum 50mg).

‌Adjustment for hepatic impairment‌:

Moderate impairment: Maximum 25mg/night.

Severe Damage: Disabled.

3. Management of missed doses and overdose of Quviviq

Missed doses can be retaken, but only once on the day. If 7 hours of sleep cannot be guaranteed after the retake, skip it.

In case of overdose‌ seek medical advice or contact a poison control center immediately.

4. Things to avoid while taking Quviviq

‌Do not drink alcohol, as it may cause serious side effects.

‌Avoid dangerous activities‌such as driving and operating machinery (until the effects of the drug are clear).

Side effects of Quviviq

See a doctor immediately if the following occurs:

‌Allergic reaction‌: Symptoms such as urticaria, severe difficulty breathing, discomfort on the face, lips, tongue, and throat may be symptoms of a severe allergic reaction.

‌Psychiatric symptoms‌: If there is a sudden major change in the patient's mood or behavior, such as an aggravation of depression or the emergence of suicidal thoughts, mental intervention should be carried out in a timely manner.

‌Complex sleep behavior‌: Driving, eating, walking, talking on the phone, or having sex without memory.

‌Movement Disorder‌: Inability to move or speak for several minutes when awake/sleeping, or experiencing hallucinations.

Common side effects include headache and drowsiness.

Contraindications for Quviviq

‌Patients with narcolepsy‌: If they often fall asleep at inappropriate times (such as sudden sleep onset during the day).

‌Allergy‌: Allergic to DaliRasen or any excipients in the tablets.

Pregnancy and lactation: There is great uncertainty about the use of thyroid drugs during pregnancy and lactation. Pregnant women who take such drugs should also inform their doctors and include them in the pregnancy registration system. Pregnant women who are lactating should fully evaluate the safety of their breastfeeding under the guidance of a doctor.

Be sure to inform your doctor of your medical history before taking this medication

Mental illness, depression or suicidal tendencies, drug or alcohol addiction, cataplexy (sudden muscle weakness), daytime sleepiness, breathing problems (including sleep apnea), abnormal liver function.

Quviviq drug interactions

Please be cautious when taking certain drugs, otherwise it may affect the concentration of the drug in the blood, which may cause side effects of the drug or reduce the effect of the original drug.

Like its combination with other sedative drugs, the effect of daliramin on drowsiness will be aggravated.

1. Combination drugs that require special vigilance

You must consult a doctor before using the following drugs in combination: opioid analgesics‌, sedative-hypnotics‌, ‌muscle relaxants‌, anti-anxiety drugs‌, and anti-epileptic drugs‌.