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Reliable channels for purchasing Lebrasin
1. Overseas purchase: Since it is not yet available in mainland China, patients can purchase it by going to countries where it is already on the market, such as Japan, the United States or Canada.
2. Purchase in Hong Kong, China or Taiwan: Lebraxant has been launched in Hong Kong, China and Taiwan, China. You can go to hospitals in the above areas for treatment, and then buy Lebraxant directly in the pharmacies of the hospital. You can also purchase Lebraxant in physical pharmacies in these areas.
3. Online pharmacies: Some legal online pharmacies may provide purchase services for Leborexen, but they usually require a doctor’s prescription and consultation in advance as to whether Leborexen can be purchased.
4. Professional pharmaceutical consulting company: You can purchase it through a professional pharmaceutical consulting company, which can provide medical information about Lebrasen, such as purchase process, version, price, etc.
When purchasing Lebraxen, you should ensure the legality and formality of the source of the drug and avoid purchasing fake and shoddy products. At the same time, follow your doctor’s guidance and recommendations to ensure the safety and effectiveness of your medication.
Tolerability of leborexan
Leborexan is generally well tolerated, with discontinuation rates of less than 1% for short-term use (two weeks) and less than 10% for long-term use (12 months). The most common side effects include daytime drowsiness, headaches, and unusual dreams. In clinical trials in patients with no history of anxiety, depression, or drug overdose, leborexan did not affect next-day function or memory unless taken with alcohol. Patients taking the 10 mg dose may have an impairment in their ability to drive. Leborexan does not need to be tapered off gradually and can be stopped suddenly because rebound insomnia and withdrawal symptoms generally do not occur.
Dose adjustment of leborexan
1. Co-administration with CYP3A inhibitors: Avoid using leborexan at the same time with strong or moderate CYP3A inhibitors. When used together with weak CYP3A inhibitors, the dose of leborexan should not exceed 5 mg per night.
2. Renal insufficiency: Patients with mild, moderate or severe renal insufficiency do not need to adjust the dosage. Patients with severe renal insufficiency may have an increased risk of drowsiness.
3. Liver function impairment: It is not recommended to adjust the dosage for patients with mild renal impairment, but patients may have an increased risk of drowsiness. Patients with moderate liver function impairment should not take more than 5 mg of Leborexant per night. Patients with severe liver function impairment are not recommended to take Leborexen.
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