达利雷生与传统失眠药有何不同

导读：达利雷生与传统失眠药在作用机制和治疗效果上存在显著的差异。无论选择达利雷生还是传统失眠药，都可能存在一定的副作用和风险。因此，在使用这些药物时，应严格遵循医生的建议，注意用药剂量和用药时间，并密切关注药物副作用。

The mechanism of action of traditional insomnia drugs

Mainly include non-benzodiazepine drugs and benzodiazepine drugs. These two types of drugs have similar hypnotic effects. They will increase GABA levels in the brain, thereby promoting sleep. Benzodiazepines are often very effective at inducing sleep, but should only be used in cases of severe insomnia or severe anxiety because of their risk of dependence.

The mechanism of action of DaliRasen

It is a dual orexin receptor antagonist that inhibits the hyperactive insomnia state by blocking the combination of orexin receptors and the wake-promoting neuropeptide orexin.这种独特的机制使得达利雷生在改善失眠症状方面有着独特的效果。

Effects of traditional insomnia drugs

Traditional drugs may change the sleep structure, resulting in residual sedative effects the next day, affecting daytime functions, and long-term use may cause dependence and withdrawal reactions. Traditional insomnia drugs may focus on a certain aspect of sleep problems, such as shortening the time it takes to fall asleep or prolonging the total sleep time, but they may not comprehensively address complex sleep disorders.

Effects of DaliRasen

DaliRasen has shown significant therapeutic effects on various forms of sleep disorders, including difficulty falling asleep, early awakening, difficulty maintaining sleep, decreased sleep quality, and sleep structure disorders. Clinical trials have shown that DaliRasen can significantly improve patients' objective indicators of falling asleep and maintaining sleep, such as the time required for sustained sleep and changes in awakening after falling asleep, and reduce patients' sleepiness the next day.

Contraindications of Daridorexant

Quviviq, Daridorexant is contraindicated in patients with narcolepsy. It is not recommended for patients with severe hepatic insufficiency. A lower maximum dose is recommended for patients with moderate hepatic insufficiency.避免达利雷生与强CYP3A4 抑制剂和中强CYP3A4诱导剂同时使用。另外，如果对达利雷生(Quviviq、Daridorexant)中的成分过敏也不应使用，以免引起过敏反应。

达利雷生作为一种处方药，需要在医生的指导下使用，以确保安全和有效性。 If you are confused about which drug to choose, it is recommended to go to a neurology or psychiatry department in a regular hospital. The doctor will make comprehensive considerations based on the patient's specific situation and needs.