达利雷生(Quviviq)的功效与作用及副作用分析

Introduction: Quviviq is an orexin receptor antagonist and a new type of anti-insomnia drug. It is suitable for the treatment of adult insomnia patients characterized by sleep attacks or sleep maintenance difficulties. It has shown good improvement effects in many insomnia patients and alleviated their insomnia troubles.

The mechanism of action of Quviviq

By blocking the binding of orexin neuropeptides (orexin A and orexin B) to their receptors, it reduces arousal drive, thereby promoting sleep. Unlike drugs that work by calming the brain, Dalitrazolin is thought to reduce overactive arousal signals to help fall asleep and stay asleep, so the drug does not alter a patient's sleep structure.

Efficacy and effects of Quviviq

Quviviq can significantly improve patients' sleep onset, sleep maintenance, and self-reported total sleep time. In clinical trials, DaliRazen helped adults with insomnia get more sleep, with improvements measured at 1 and 3 months. Studies have shown that Dali Lasen can improve various insomnia symptoms such as difficulty falling asleep, frequent awakenings during sleep, excessive dreams, and easy awakening, and improve the quality of sleep.

Side effects of Quviviq

The more common side effects of Quviviq are headache, dizziness, drowsiness, fatigue, nausea, and vomiting. It is recommended to take rest while taking the medication, avoid driving and other activities that require complete mental alertness the next day, and drink plenty of water to reduce nausea and vomiting. In addition, you must go to bed at a regular time and get up at a regular time to avoid sleeping during the day or sleeping for too long during the day. If the side effects are severe or last too long, you should consult your doctor. The dose may need to be adjusted or other treatment options may need to be changed.

Recommended dosage

The recommended dosage range of Quviviq (Daridorexant) is 25mg-50mg, which needs to be taken orally within 30 minutes before going to bed, and should be taken no more than once a night. Before taking the medicine, be sure to ensure that there are at least 7 hours before you plan to wake up. If taken with or shortly after a meal, it may delay the time it takes to fall asleep. Try to avoid smoking and drinking while taking the medicine, and do not drink caffeinated beverages such as coffee, tea, etc. at night.

(Note: The above dosage and dosage reference are from the U.S. FDA drug instructions. The usage and dosage are for reference only. The specific dosage needs to be subject to medical advice)

Precautions

Daliferazen should be avoided from being used at the same time with strong CYP3A4 inhibitors. If used at the same time as a moderate CYP3A4 inhibitor, the recommended maximum dose of daliferason is 25 mg per night. Grapefruit or grapefruit juice should be avoided in the evening as they may interfere with drug metabolism.

During the use of DaliRasen, patients should follow the doctor's instructions and pay attention to the dosage and use time of the drug to ensure safe and effective treatment. If you have any questions or concerns, you should consult your doctor or pharmacist promptly.