罗氟司特国内有吗？

Roflumilast is an oral selective phosphodiesterase-4 (PDE4) inhibitor developed by Nycomed, a new chronic obstructive pulmonary disease (COPD) treatment drug for the treatment of asthma and chronic obstructive pulmonary disease. Roflumilast is mainly expressed on inflammatory cells related to asthma, including eosinophils, neutrophils and mast cells. The drug can specifically act on a certain enzyme involved in smooth muscle contraction, prevent the degradation of cAMP, thereby blocking the transmission of pro-inflammatory response signals. It has anti-inflammatory activity and has achieved good clinical results in the treatment of asthma and chronic obstructive pulmonary disease. It can also significantly delay the worsening of respiratory symptoms and greatly improve the patient's quality of life.

Roflumilast has been shown to inhibit inflammation associated with COPD in a novel mode of action. As a once-daily oral tablet, roflumilast is not only the first of a new treatment for severe COPD but also the first oral anti-inflammatory drug for COPD patients. Its unique properties could help better treat patients with COPD: When combined with a bronchodilator to treat patients with the most severe forms of COPD, roflumilast provides the additional benefit of further reducing symptoms and rates of disease exacerbations, making it the first drug to target a specific phenotype of COPD in patients with severe airflow limitation associated with chronic cough and phlegm and a history of recurrent disease exacerbations.

Is it available in China? Currently, roflumilast is not marketed in China and is not eligible for medical insurance. In other words, if patients want to purchase the drug, they must go abroad to purchase it. Traveling abroad to buy medicines is a long journey and requires a lot of manpower and material resources. Coupled with the huge medical expenses, many patient families are overwhelmed. However, according to Medical Companion Travel, 500μg*90 tablets of roflumilast costs approximately $2,850 per box. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about roflumilast, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.