利伐沙班片会引发肢体疼痛吗？

Limb pain is usually caused by the side effects of rivaroxaban tablets, but the specific mechanism of action is not yet clear and may be related to pharmacological effects. If the pain is severe, the patient can handle it under the guidance of a doctor.

Pharmacological effects of rivaroxaban tablets

Rivaroxaban is a direct, highly selective and competitive factor Xa inhibitor that inhibits the activity of free and fibrin-bound factor

Rivaroxaban has no direct effect on thrombin, but inhibits the formation of thrombin by inhibiting the activity of factor Xa, thereby hindering the formation of fibrin, and ultimately inhibits the formation and expansion of thrombus.

Because rivaroxaban can selectively inhibit thrombin, its pharmacological effects are more targeted, effectively reducing thrombin content and thereby inhibiting the activity of the coagulation mechanism.

Rivaroxaban tablets

1. Bleeding: The main cause of bleeding caused by rivaroxaban is that it directly inhibits the FXa factor and prolongs the coagulation time. In addition, rivaroxaban can cause thrombocytopenia, and thrombocytopenia can also cause bleeding. In elderly patients, due to reduced liver and kidney function, hemorrhagic adverse reactions of rivaroxaban are more prominent.

2. Hepatobiliary system diseases: jaundice, cholestasis, hepatitis (including liver cell damage).

3. Musculoskeletal and connective tissue diseases: limb pain, muscle spasm.

4. Other side effects: such as abdominal pain, fatigue, dizziness, anxiety, depression, insomnia, skin itching, etc.

How to deal with limb pain

1. Adjust medication: If the patient has severe pain after taking rivaroxaban tablets, he or she can stop taking the medication or switch to other medications under the guidance of a doctor.

2. Use painkillers: Patients can use ibuprofen, celecoxib, naproxen and other drugs as directed by the doctor to relieve pain and relieve pain symptoms.

3. Hot compress: Pain symptoms can be relieved locally by using a hot towel to apply hot compress. Care should be taken to avoid burns.

4. Other methods: Pain symptoms can also be improved through acupuncture, massage and other methods.

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