利伐沙班治疗静脉血栓需要吃多久?
Rivaroxaban (Xarelto) is an oral, bioavailable factor Xa inhibitor that selectively blocks the active site of factor Xa and does not require cofactors (such as antithrombin III) to exert activity. Rivaroxaban (Xarelto) activates factor X into factor Xa (FXa) through endogenous and exogenous pathways, playing an important role in the coagulation cascade.那治疗静脉血栓需要吃多久?
It takes at least 3-6 months for rivaroxaban (Xarelto) to dissolve thrombosis. When rivaroxaban (Xarelto) is used early, most venous thrombosis will disappear after one month. However, as research data gradually increases, it is found that if you only take rivaroxaban (Xarelto) for one month, many deep vein thrombosis are easy to relapse and the recurrence rate is high. Therefore, in current clinical practice, it is generally recommended to take rivaroxaban (Xarelto) orally for more than three months and within half a year, and at the same time, regular color ultrasound follow-up is required.
If the blood clot still exists, especially if deep vein thrombosis is accompanied by pulmonary embolism, it is generally recommended to take rivaroxaban (Xarelto) orally for 6-12 months to avoid the recurrence of deep vein thrombosis or pulmonary embolism. Nowadays, Rivaroxaban (Xarelto) is also used clinically for the treatment of atrial fibrillation with non-valvular disease to prevent the formation of thrombus in the heart. Generally, such patients take this drug for a long time, at least 12 months or more, to prevent the formation of thrombus around the heart valve.
Rivaroxaban Precautions
Patients with severe allergy to rivaroxaban (Xarelto) or any of its components, patients with clinically significant active bleeding, and patients with liver disease with coagulation abnormalities and clinically relevant risk of bleeding should not be treated with this product.
Treatment with rivaroxaban (Xarelto) may cause harm to the fetus, so patients should take effective contraceptive measures during treatment with this drug. Pregnant and lactating women should not use this drug for treatment.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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