利伐沙班片是什么药？主治什么病？

Rivaroxaban is a new direct oral anticoagulant drug. In recent years, it has been found that it plays an important role in anticoagulation and antithrombosis in a variety of diseases, and it has potential myocardial protection. In clinical practice, this drug is mainly used to treat venous thrombosis in adults. It mainly exerts biological activity by directly inhibiting factor Xa in the coagulation process. It not only acts on free factor Xa, but also inhibits bound factor

In a domestic study, 60 cases of deep vein thrombosis prevention after hip replacement were given rivaroxaban and low-molecular-weight heparin respectively. The results showed that the incidence of DVT in the rivaroxaban group was significantly reduced, and the incidence of bleeding events was significantly lower than that of the low-molecular-weight heparin group. The control of platelet and coagulation levels was equivalent to that of low-molecular-weight heparin.

In a study comparing rivaroxaban and warfarin for the treatment of early intravascular thrombosis and stent implantation in the treatment of acute iliac and femoral vein thrombosis, foreign researchers showed that rivaroxaban showed equivalent effectiveness and safety to warfarin. A domestic meta-analysis of 24 included articles and 40,001 patients showed that 7 new oral anticoagulants are more effective than low-molecular-weight heparin in preventing venous thromboembolism after total hip and knee replacement, and rivaroxaban is more effective in comparing similar drugs.

Another meta-analysis study that included 5 RCTs and 4737 patients showed that compared with heparin/low molecular weight heparin + vitamin K antagonist, the rivaroxaban group has a significantly lower recurrence rate in deep vein thrombosis such as pulmonary embolism, and does not increase the risk of major bleeding, death, etc. Based on the results of previous clinical trials, the overall therapeutic effect of Rivaroxaban is relatively obvious, and the medication is relatively safe. Patients can purchase and use it with confidence.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

Recommended related articles: