拜耳利伐沙班用多久停药?
(Rivaroxaban) is a new oral anticoagulant that can directly and selectively bind to Xa to inhibit the conversion of prothrombin into thrombin, thereby exerting an anti-thrombotic effect. Compared with the traditional anticoagulant drug vitamin antagonist, rivaroxaban is mainly excreted through the biliary tract and kidneys, so it is not easily affected by diet and drugs. At the same time, rivaroxaban has a quick onset of action, high oral bioavailability, and is safer and more convenient. Based on the above characteristics, higher doses (10-20 mg once daily) of rivaroxaban have been widely used in the prevention and treatment of various thromboembolic diseases.
Bayer Group is one of the world's famous multinational pharmaceutical companies. In 2006, Bayer entered the Chinese market through the acquisition of Dongsheng Technology. The aflibercept produced by Bayer has obvious curative effects and patients can buy and use it with confidence. So, for patients, how long does it take to stop taking Bayer rivaroxaban?
The recommended dose of rivaroxaban (i.e. Xarelto) is 10 mg/time orally, once/day. When the wound has stopped bleeding, the patient's first medication should be administered between 6 and 10 hours after surgery. Under normal circumstances, as long as the patient is not allergic to any ingredients in Rivaroxaban tablets, can continue to benefit from it, and tolerates the drug without any toxic reactions, in principle, it can be taken for a long time. Of course, if some uncontrollable factors occur during this period, the patient needs to consider whether to continue taking the medication based on the doctor's advice.
Studies have shown that when rivaroxaban is used concurrently with strong inhibitors of CYP3A4 and P-gp, the plasma concentration of rivaroxaban will increase, so there is a risk of bleeding. Therefore, simultaneous use of rivaroxaban and strong inhibitors of CYP3A4 and P-gp should be avoided. Erythromycin, clarithromycin, and fluconazole have moderate effects on rivaroxaban exposure and should be used with caution. Coadministration of rivaroxaban with the strong CYP3A4 inducer rifampicin will also lead to decreased plasma concentrations, and caution should be exercised when coadministered with strong CYP3A4 inducers.
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Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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