拜耳拜瑞妥使用说明

Bayer Group, a German pharmaceutical company, is one of the well-known Fortune 500 companies. Bayer's Xarelto is approved for the treatment of patients with venous thrombosis. The following are the instructions for use of Bayer compiled by Medical Companion Travel:

1. To prevent venous thrombosis in adult patients undergoing elective hip or knee replacement surgery: the recommended dose is Xarelto 10 mg orally, once daily. If the wound has stopped bleeding, the first medication should be taken between 6 and 10 hours after surgery. For patients who have undergone major hip surgery, the recommended treatment course is 35 days. For patients who have undergone major knee surgery, the recommended treatment course is 12 days. If a missed dose occurs, the patient should take Xarelto immediately and continue to take the drug once a day the next day.

2. Treat venous thrombosis (DVT) in adults and reduce the risk of acute DVT recurrence and PE: The recommended initial treatment dose for acute DVT is 15 mg twice a day for the first three weeks, and the subsequent dose for maintenance treatment and reducing the risk of DVT recurrence and PE is 20 mg once a day. The dosage regimen of Xarelto Tablets for DVT, after carefully evaluating the treatment benefits and bleeding risks, the duration of treatment should be determined according to individual circumstances. Short-term treatment (3 months) should be based on transient risk factors (eg, recent surgery, trauma, immobilization), and long-term treatment should be based on permanent risk factors or idiopathic DVT. There is insufficient experience with Xarelto for more than 12 months for this indication. 

3. For use in adult patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism: the recommended dose is 20 mg once a day, which is also the maximum recommended dose. For patients with low body weight and advanced age (>75 years old), doctors can use 15 mg once a day as appropriate based on the patient's condition. In situations where the benefits of preventing stroke and systemic embolism outweigh the risks of bleeding, long-term treatment should be considered. If a missed dose occurs, the patient should take Xarelto immediately and continue receiving the once-daily dose the next day. The dose should not be doubled in one day to make up for a missed dose.

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