德国拜耳利伐沙班怎么样
It was launched in Canada and the European Union in 2008 and in my country on June 18, 2009. It was approved by the FDA on November 14, 2011 for the prevention of stroke or systemic embolism in patients with non-valvular atrial fibrillation. So what about rivaroxaban produced by Bayer in Germany?
Rivaroxaban, originally sold under the trade name Xarelto, is an anticoagulant drug (blood thinner) used to treat and prevent blood clots. It is used to treat deep vein thrombosis and pulmonary embolism, and to prevent blood clots in atrial fibrillation and after hip or knee surgery. Rivaroxaban can interrupt the intrinsic and extrinsic pathways of the coagulation cascade by inhibiting factor xa, inhibiting thrombin generation and thrombosis. Rivaroxaban does not inhibit thrombin and has no proven effect on platelets. A dose-dependent inhibition of factor xa activity by rivaroxaban has been observed in humans.
Bayer, headquartered in Leverkusen, Germany, has 750 production plants in 200 locations on six continents; it has 120,000 employees and 350 branches in almost every country in the world. Polymers, medicine and health care, chemical industry and agriculture are the company's four pillar industries. The company's product categories exceed 10,000 types. The company has produced aspirin, heroin and other products.
A newly published study shows that the new anticoagulant drug rivaroxaban from Bayer Healthcare of Germany can effectively reduce the formation of venous thrombosis in patients after major orthopedic surgery, and its efficacy is better than the current standard treatment of enoxaparin.
The recommended dose of rivaroxaban is 10 mg orally administered once daily. If the wound has stopped bleeding, the first medication should be administered between 6-10 hours after surgery. The length of treatment is determined by each patient's risk of VTE, i.e. by the type of orthopedic surgery the patient has undergone. For patients undergoing major hip surgery, a recommended course of treatment is 5 weeks. For patients undergoing major knee surgery, a recommended course of treatment is 2 weeks. If a missed dose occurs, the patient should take rivaroxaban immediately and continue taking the drug once a day the next day. Patients can take it with meals or alone.
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