利伐沙班该如何服用？

How should I take it to treat venous thrombosis?

1. Rivaroxaban 10mg can be taken with food or alone. Rivaroxaban 15 mg or 20 mg tablets should be taken with food.

2. To prevent venous thrombosis in adult patients undergoing elective hip or knee replacement surgery:

The recommended dose is rivaroxaban 10 mg orally once daily. If the wound has stopped bleeding, the first dose of medication should be between 6 and 10 hours after surgery.

3. For patients undergoing major hip surgery, the recommended treatment course is 35 days. For patients undergoing major knee surgery, the recommended course of treatment is 12 days.

4. If a missed dose occurs, the patient should take rivaroxaban immediately and continue to take the medicine once a day the next day.

5. Treat DVT and reduce the risk of acute DVT recurrence and PE.

The recommended dose for initial treatment of acute DVT is 15 mg twice daily for the first three weeks, followed by 20 mg once daily for maintenance treatment and to reduce the risk of recurrent DVT and PE.

6. If a missed dose occurs during 15 mg twice daily treatment (days 1-21), the patient should take rivaroxaban immediately to ensure that 30 mg of rivaroxaban is taken daily. In this case, it may be necessary to take two 15 mg tablets at once. Thereafter, regular 15 mg twice daily dosing should be continued as recommended.

7. If a missed dose occurs during 20 mg once-daily treatment (day 22 and thereafter), the patient should take rivaroxaban immediately, and then continue to receive once-daily dosing at the recommended dose. The dose should not be doubled in one day to make up for a missed dose.

8. Used in adult patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism.

The recommended dose is 20 mg once a day, which is also the maximum recommended dose. For patients with low body weight and advanced age (>75 years old), doctors can use 15 mg once a day as appropriate based on the patient's condition.

9. When the benefits of rivaroxaban in preventing stroke and systemic embolism outweigh the risk of bleeding, long-term treatment should be given.

10. If a missed dose occurs, the patient should take it immediately and continue to receive the once-daily dose the next day. The dose should not be doubled in one day to make up for a missed dose.