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Apremilast is the first oral medication to treat psoriasis, and studies show that long-term use of Apremilast ec for approximately 16 weeks can improve the appearance of patients' skin. It is a pioneering oral drug that is a selective phosphodiesterase 4 (PDE-4) inhibitor. It was launched in the United States in 2014 and in Europe in 2015. This drug is a small molecule phosphodiesterase 4 (PDE4) inhibitor.

So, what are the contraindications for taking Apremilast tablets? Apremilast is contraindicated in patients who are known to be allergic to the prodrugs or any excipients in the preparation; pay attention to diarrhea, nausea and vomiting during treatment, and if symptoms are severe, consider reducing the dose of Apremilast or discontinuing the drug; family members pay attention to the emergence or worsening of depression, suicidal thoughts or other mood changes in the patient; if unexplained or clinically significant weight loss occurs, evaluate the weight loss and consider discontinuing Apremilast. The tablets of Apremilast cannot be crushed, split, or chewed, and the drug is banned for use by pregnant women in the European Union but can be used by pregnant women in the United States.

So, does Apremilast have any side effects? Apremilast is the first oral medication approved for the treatment of psoriasis in the past 20 years. Compared with placebo, patients treated with Apremilast tablets showed improvements in the signs and symptoms of PsA, including tender and swollen joints and physical function. But the drug also has side effects. Diarrhea, nausea, and headache are the most common side effects in patients with psoriatic arthritis. Diarrhea, nausea, upper respiratory tract infections, and headaches, including tension headaches, are the most common side effects in patients with psoriasis.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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