阿普斯特是治疗什么病的药？正确服用方法是什么？

Apremilast tablets were launched in the United States in March 2014. The drug is a phosphodiesterase-4 (PDE-4) inhibitor. Apremilast tablets are a brand-name prescription drug that can be taken orally. This drug is produced and developed by Celgene Corporation. Today let’s take a closer look at what disease it is used to treat? What is the correct way to take it?

Apremilast is the first oral drug approved for psoriatic arthritis in the past 15 years and has been approved by the U.S. FDA and European regulatory agencies. The indications for Apremilast tablets mainly include patients with psoriasis and adults with active psoriatic arthritis. This drug reduces the activity in the immune system that causes chronic inflammation and plaque formation, thereby reducing skin flaking and scaling. Apremilast tablets are the first oral drug approved for the treatment of psoriasis in the past 20 years. It has been proven to be able to achieve clinically significant and lasting improvement in patients' condition. As a small molecule compound, Apremilast tablets are administered orally and are convenient for patients to take and carry.

What is the correct way to take Apremilast? Apremilast has a short half-life, so if treatment needs to be interrupted, the safety factor is high. The titration to the recommended dose needs to be carried out according to time. The first day: 10 mg in the morning; the second day: 10 mg in the morning and 10 mg in the evening; the third day: 10 mg in the morning and 20 mg in the evening. The fourth day: 20 mg in the morning and 20 mg in the evening; the fifth day: 20 mg in the morning and 30 mg in the evening; the sixth day and beyond: 30 mg twice a day. This method of taking Apremilast can reduce the risk of gastrointestinal symptoms. Patients should not change the dosage and usage at will to avoid intolerance reactions. The main adverse reactions of this drug in the treatment of psoriatic arthritis are diarrhea, nausea and headache.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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