氯法齐明治疗效果好吗?哪里能买到氯法齐明?
At this stage, clofazimine is mainly used as the drug of choice for the treatment of neoplastic leprosy. It was launched in the United States in 1986. Clofazimine contains brown-red or reddish-brown suspension oily liquid, the main component is clofazimine, and is a commonly used capsule. The mechanism of action is to interfere with nucleic acid metabolism and inhibit bacterial protein synthesis.
The absorption rate of clofazimine after oral administration of particulate crystals is 50% to 70%, and the tissue drug concentration is higher than the blood drug concentration; its elimination half-life is 70 days. This product is one of the combination therapy drugs. The trial is to explore the therapeutic effect of adding clofazimine on the basis of chemotherapy in the treatment of multi-drug-resistant tuberculosis. Methods: 172 patients with multidrug-resistant tuberculosis were selected and randomly divided into 80 patients in the control group and 92 patients in the observation group. On the basis of traditional drug treatment, clofazimine was added for intensification. After treatment, the efficacy and complications of the two groups of patients were determined. Results After 6 months of treatment, sputum bacteria and lesions were examined. In the observation group, 48 cases had sputum bacteria that became negative, and in the control group, 21 cases had sputum bacteria that became negative. After 12 months of treatment, in the observation group, 55 cases of sputum bacteria became negative; in the control group, 26 cases had sputum bacteria that became negative. After the course of treatment, 85 cases of lesions in the observation group improved, with an improvement rate of 92.4%; 38 cases of lesions in the control group improved, with an improvement rate of 47.5%. Conclusion Clofazimine combined with capreomycin, clarithromycin, amoxicillin-clavulanate potassium, prothionamide and other traditional drugs has good efficacy in the treatment of multi-drug-resistant tuberculosis, and can significantly improve the patient's sputum negative conversion and lesion improvement rate without increasing the occurrence of complications.
So, where can I buy clofazimine? At present, clofazimine has been included in medical insurance. Domestic patients can use medical insurance to purchase this product in hospital pharmacies. You can also learn about the overseas version of clofazimine through Medical Companion Travel, which is directly mailed by the pharmaceutical factory and is more cost-effective. Medical Travel is a professional overseas medical service organization in China. It is trusted by many patients and can be cooperated with confidence. Since overseas drugs are affected by exchange rate fluctuations, the price of clofazimine is not fixed. It is recommended to consult the medical companion passenger service to understand the cost of clofazimine and the drug purchase process.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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